三带喙库蚊
银纳米粒子
白纹伊蚊
生物
登革热
载体(分子生物学)
硝酸银
日本脑炎
核化学
埃及伊蚊
植物
幼虫
材料科学
病毒学
化学
纳米颗粒
脑炎
生物化学
纳米技术
病毒
基因
重组DNA
作者
Marimuthu Govindarajan,Mohan Rajeswary,Kaliyan Veerakumar,Udaiyan Muthukumaran,S.L. Hoti,Giovanni Benelli
标识
DOI:10.1016/j.exppara.2015.12.011
摘要
Mosquitoes (Diptera: Culicidae) represent a key threat for millions of people worldwide, since they act as vectors for devastating parasites and pathogens. In this scenario, eco-friendly control tools against mosquito vectors are a priority. Green synthesis of silver nanoparticles (AgNP) using a cheap, aqueous leaf extract of Anisomeles indica by reduction of Ag+ ions from silver nitrate solution has been investigated. Bio-reduced AgNP were characterized by UV–visible spectrophotometry, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive spectroscopy (EDX) and X-ray diffraction analysis (XRD). The acute toxicity of A. indica leaf extract and biosynthesized AgNP was evaluated against larvae of the malaria vector Anopheles subpictus, the dengue vector Aedes albopictus and the Japanese encephalitis vector Culex tritaeniorhynchus. Both the A. indica leaf extract and AgNP showed dose dependent larvicidal effect against all tested mosquito species. Compared to the leaf aqueous extract, biosynthesized AgNP showed higher toxicity against An. subpictus, Ae. albopictus, and Cx. tritaeniorhynchus with LC50 values of 31.56, 35.21 and 38.08 μg/mL, respectively. Overall, this study firstly shed light on the mosquitocidal potential of A. indica, a potential bioresource for rapid, cheap and effective AgNP synthesis.
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