医学
狼牙棒
强直性脊柱炎
银屑病性关节炎
类风湿性关节炎
心肌梗塞
银屑病
不稳定型心绞痛
内科学
心力衰竭
不利影响
皮肤病科
传统PCI
标识
DOI:10.1016/j.cgh.2024.02.020
摘要
Immune-mediated inflammatory disorders (IMIDs) including inflammatory bowel disease (IBD), rheumatoid arthritis (RA), psoriasis/psoriatic arthritis (PSO), and ankylosing spondylitis (AS), are associated with increased risk of major adverse cardiovascular events (MACE). There is uncertainty regarding the cardiovascular safety of newer medications for IMIDs such as biologics and small molecules (anti-IL-23, anti-IL-12/23, anti-TNFs, and JAKi). This network meta-analysis pooled 40 studies (36 RCTs) that reported MACE (myocardial infarction, cerebrovascular accident, unstable angina, cardiovascular death, or heart failure) in patients with IMIDs.
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