医学
败血症
氧化应激
心肌病
重症监护医学
发病机制
器官功能障碍
生物信息学
免疫学
心脏病学
心力衰竭
内科学
生物
出处
期刊:PubMed
日期:2022-12-01
卷期号:34 (12): 1337-1341
标识
DOI:10.3760/cma.j.cn121430-20220901-00811
摘要
Sepsis is currently defined as a life-threatening multiple organ dysfunction caused by host dysregulated response to infection, with high morbidity and mortality in intensive care units. Patients with sepsis are often complicated with cardiac dysfunction known as septic cardiomyopathy (SCM). The occurrence of SCM is related to the high mortality of patients, which has been closely concerned for a long time, and is also one of the challenges to be solved in the systematic treatment of sepsis. A large number of studies have shown that oxidative stress contributes to the pathogenesis of SCM. The role of oxidative stress in SCM and the potential treatment measures for redox imbalance are discussed in this paper.
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