连锁不平衡
流苏
联动装置(软件)
遗传关联
人口
关联映射
软件
计算机科学
数据挖掘
生物
遗传学
基因型
扎梅斯
农学
程序设计语言
单倍型
单核苷酸多态性
人口学
社会学
基因
作者
Peter J. Bradbury,Zhiwu Zhang,Dallas E. Kroon,Terry M. Casstevens,Yogesh Ramdoss,Edward S. Buckler
出处
期刊:Bioinformatics
[Oxford University Press]
日期:2007-06-22
卷期号:23 (19): 2633-2635
被引量:5537
标识
DOI:10.1093/bioinformatics/btm308
摘要
Association analyses that exploit the natural diversity of a genome to map at very high resolutions are becoming increasingly important. In most studies, however, researchers must contend with the confounding effects of both population and family structure. TASSEL (Trait Analysis by aSSociation, Evolution and Linkage) implements general linear model and mixed linear model approaches for controlling population and family structure. For result interpretation, the program allows for linkage disequilibrium statistics to be calculated and visualized graphically. Database browsing and data importation is facilitated by integrated middleware. Other features include analyzing insertions/deletions, calculating diversity statistics, integration of phenotypic and genotypic data, imputing missing data and calculating principal components.
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