生物相容性
材料科学
层状双氢氧化物
纳米技术
骨愈合
腐蚀
模拟体液
插层(化学)
合金
生物医学工程
冶金
复合材料
化学工程
化学
医学
工程类
无机化学
外科
氢氧化物
扫描电子显微镜
作者
M. Richetta,Chiara de Crescenzo,Riccardo Narducci,Roberto Montanari,Alessandra Varone
出处
期刊:Key Engineering Materials
日期:2023-12-05
卷期号:967: 121-130
摘要
This work briefly discusses the applications of Layered Double Hydroxides (LDHs) to medicine and presents a study regarding the growth of LDHs on the biodegradable AZ31 alloy foreseen to manufacture a rib-fixator. Mg is one of the most investigated metallic materials for biomedical applications owing to its high biocompatibility and osteointegration, as well as a value of the elastic modulus close to that of human bone. Since Mg is essential for metabolism, when it degrades forming Mg 2+ ions, it promotes healing and growth of bone tissue. Experiments have been carried out to grow LDHs on the alloy surface in view to retard corrosion in human body and intercalate drugs to be released in-situ, with anti-inflammatory, analgesic, and antimicrobial action.
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