mTORC1型
脂肪生成
甾醇调节元件结合蛋白
PI3K/AKT/mTOR通路
转录因子
生物
细胞生物学
信号转导
癌症研究
生物化学
脂质代谢
基因
作者
Inan Bakan,Mathieu Laplante
标识
DOI:10.1097/mol.0b013e328352dd03
摘要
The discovery of a connection between mTORC1 and SREBP-1 opens a new chapter in our understanding of the molecular mechanisms regulating de-novo lipogenesis. A better comprehension of these mechanisms is key for the development of new tools to treat NAFLD and its complications.
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