医学
射血分数
心源性休克
冠状动脉疾病
内科学
心脏病学
心肌梗塞
心力衰竭
传统PCI
冲程(发动机)
机械工程
工程类
作者
Charbel Abi Khalil,Kadhim Sulaiman,Nidal Asaad,Khalid F Alhabib,Alawi A. Alsheikh‐Ali,Mohammed Jameesh,Mohammed Al‐Jarallah,Bassam Bulbanat,Wael Almahmeed,Mustafa Ridha,Nooshin Bazargani,Haitham Amin,Ahmed Al‐Motarreb,Husam AlFaleh,Prashanth Panduranga,Ziyad Mahfoud,Jassim Al Suwaidi
出处
期刊:Current Vascular Pharmacology
[Bentham Science]
日期:2020-09-17
卷期号:18 (6): 644-651
被引量:1
标识
DOI:10.2174/1570161118666191231114203
摘要
The prognostic impact of beta-blockers (BB) in coronary artery disease (CAD) is controversial, especially in the post-reperfusion era. We studied in-hospital cardiovascular events in patients hospitalized for acute HF, a previous history of CAD and a left ventricular ejection fraction (LVEF) ≥40%, in relation to BB on admission; and 1-year outcome in relation to BB on discharge, in the GULF aCute heArt failuRe (GULF-CARE) registry. From a total of 5005 patients included in the GULF-CARE registry, 303 patients with a previous history of CAD and a LVEF ≥40% on BB were propensity-matched to 303 patients without BB on admission. In-hospital mortality (OR= 0.82; 95% CI [0.35-1.94]), stroke and cardiogenic shock were not reduced by BB. On discharge, 306 patients on BB, including the ones newly diagnosed with myocardial infarction as a precipitating cause of HF, were propensity-scored matched with 306 patients without BB. Mortality (OR= 0.86; 95%CI [0.51-1.45], hospitalization for HF or PCI/CABG at 1 year were also not reduced by BB at discharge. In summary, our data show that BB have a neutral effect on in-hospital and 1-year outcomes in acute heart failure patients with a previous history of CAD and a LVEF ≥40%.
科研通智能强力驱动
Strongly Powered by AbleSci AI