医学
阵发性运动障碍
运动障碍
病理生理学
内科学
运动障碍
作者
Anna Corradi,Pierluigi Valente,Caterina Michetti,Fabio Benfenati
出处
期刊:Springer International Publishing eBooks
[Springer Nature]
日期:2021-01-01
卷期号:: 95-108
被引量:1
标识
DOI:10.1007/978-3-030-53721-0_7
摘要
Paroxysmal dyskinesias are a group of hyperkinetic movement disorders characterized by episodes of dystonia, chorea, athetosis, and ballism that appear isolated or in combination without loss of consciousness. We can differentiate various forms of paroxysmal dyskinesia based on genotypic and phenotypic features: Paroxysmal kinesigenic dyskinesia, paroxysmal non-kinesigenic dyskinesia, and paroxysmal exercise-induced dyskinesia. However, all disorders display common traits, such as the paroxysmal nature and the presence of triggering factors. The episodic nature of these diseases suggests that they result from neuronal network instability and from a general state of hyperexcitability. This augmented excitability is also responsible for the epileptic phenotype that is often associated with paroxysmal dyskinesia.
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