To explore the correlativity of meridians and acupoints with fascial system.The lines and beads-like structures seen by fasciaology and scanning connective tissue, were combined with traditional meridians and collaterals, and acupoints to investigate channels, collaterals and acupoints.The high correlativity of the meridians and acupoints with the fascial system was found.The concept, functions, clinical application and mechanisms of meridians and acupoints can be preliminarily explained.