渗出液
伤口愈合
硫化氢
控制释放
内生
医学
化学
药理学
外科
病理
生物化学
有机化学
硫黄
作者
Lu Chen,Youzhen Li,Wenchao Zhu,Yang Yan,Kai Li,Qingtao Li,Meng Gao
出处
期刊:ACS applied bio materials
[American Chemical Society]
日期:2023-01-17
卷期号:6 (2): 674-680
被引量:2
标识
DOI:10.1021/acsabm.2c00919
摘要
Hydrogen sulfide (H2S) as an endogenous gasotransmitter plays a critical role in promotion of wound healing. However, the current H2S release system lacks the in situ monitoring ability, which may lead to insufficient or overdose release of H2S and serious side effects. Herein, we develop a self-monitoring theranostic probe TPATCF-S, which can quickly release H2S under water stimuli associated with a self-monitoring ability by a color change from colorless to deep blue. With a full thickness dermal defect as a model, the TPATCF-S absorbed on alginate dressings can be used for wound exudate-responsive release of H2S to efficiently promote skin wound healing.
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