中肠
粘虫
内质网
化学
内膜系统
作用机理
超微结构
细胞质
立体化学
细胞生物学
生物化学
体外
生物
解剖
生殖器鳞翅目
植物
高尔基体
幼虫
作者
Bo Zhou,Lulu Liu,Wangyu Zhao,Lijuan Han,Aijuan Li,Chun Yan Zhao,Wenjun Wu,Jiwen Zhang
标识
DOI:10.1080/10286020.2022.2123318
摘要
A series of 4-(propargyloxy) benzenesulfonamide derivatives with different substituents on the benzene ring were synthesized and evaluated for their insecticidal activity. Some of the compounds showed good insecticidal activity against Mythimna separata, and the LC50 value of the most active compound B2.5 was 0.235 mg/ml. Ultrastructural changes in the midgut epithelial cells of Mythimna separata were observed using transmission electron microscopy, and severe structural damage was found in microvilli, mitochondria and rough endoplasmic reticulum. It indicates that the possible site of action of these benzenesulfonamides is the cytoplasmic membrane and endomembrane system of the midgut epithelial cells. The above provides a basis for the development of novel insecticidal active compounds with a novel mechanism of action.
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