Impact of intestinal flora on calcium oxalate stones.

Kidney stone is one of the common diseases of the urinary system. About 80% of kidney stones are mainly composed of calcium oxalate. As a huge bacterial network, the interaction of gut microbes is complex. Intestinal microbes may play a role in the pathogenesis and prevention of kidney stones. The intestinal flora of patients with calcium oxalate stones possess unique distribution of gut microbes. Oxalobacter formigenes, Bifidobacterium, Lactobacillus, Escherichia coli, and Providencia reteri bacteria are closely related to calcium oxalate stones, which provides new ideas for the prevention and treatment of urinary stones.