Generation and Reaction of (N-Aryltrifluoroacetimidoyl)zinc Halide

Abstract (N-Aryltrifluoroacetimidoyl)zinc halides were easily generated at room temperature by the oxidative addition of imidoyl halides to activated zinc powder. [N-(2,6-Dichlorophenyl)- and N-(2,6-dimethylphenyl)trifluoroacetimidoyl]zinc halides react with aldehydes to give the corresponding alcohols smoothly in good to excellent yields. These adducts could be readily transformed to the α-amino ketones.