Research status and future of goal-directed fluid therapy

Fluid therapy plays an important role in maintaining the stability of vital signs and the good perfusion of tissues.Therefore, it is the basis for treatment of diseases.The purpose of fluid therapy is to keep the patient′s effective circulating volume, increase cardiac output, and ensure adequate tissue perfusion, which may facilitate the transport of oxygen and nutrients.Perioperative fluid therapy has gone through the progress from choosing the type of liquid to reforming the mode of fluid treatment.Since the concepts of fast track surgery and precision medicine appeared, the anesthesiologists and surgeons have pay more attention to the goal-directed fluid therapy(GDFT). GDFT aims to maintain organ perfusion and oxygen transport of tissues by regulating the amount of fluid on basis of a physiological index.As a new fluid therapy, GDFT contributes to maintaining oxygen delivery and reducing both morbidity and mortality.This article reviews the progress and challenges for GDFT. Key words: Fluid therapy; Goal-directed fluid therapy; Hemodynamics