纳米技术
微尺度化学
材料科学
微流控
金属有机骨架
嵌入
计算机科学
化学
人工智能
数学
数学教育
吸附
有机化学
作者
Shujun Zhang,Qian Lin,Yanlin Song,Jia‐Qi Huang,Miaomiao Chen,Runxian Ouyang,Si‐Yang Liu,Zong Dai
出处
期刊:Chemosensors
[MDPI AG]
日期:2023-08-02
卷期号:11 (8): 429-429
被引量:5
标识
DOI:10.3390/chemosensors11080429
摘要
Metal–organic frameworks (MOFs), constructed by coordination between metal-containing nodes and organic linkers, are widely used in various fields due to the advantages of tunable pores, diverse functional sites, stable structure, and multi-functionality. It should be noted that MOF-based materials play a major role in glucose detection, serving as a signal transducer or functional substrate for embedding nanoparticles/enzymes. Diabetes is one of the most common and fast-growing diseases worldwide, whose main clinical manifestation is high blood sugar levels. Therefore, accurate, sensitive, and point-of-care glucose detection is necessary. This review orderly introduces general synthetic strategies of MOF-based materials (pristine MOF, nanoparticles, or enzymes-modified MOF and MOF-derived materials) and detection methods (electrochemical and optical methods) for glucose detection. Then, the review refers to the novel MOF-based glucose detection devices (flexible wearable devices and microfluidic chips), which enable non-invasive continuous glucose monitoring or low-cost microscale detection. On the basis of describing the development of glucose sensors based on MOF materials in the past five years, the review presents merits, demerits, and possible improvements of various detection methods.
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