皮肤干燥
医学
特应性皮炎
皮肤病科
干燥
尿布皮炎
氧化应激
敏感皮肤
免疫学
内科学
作者
Adelaide A. Hebert,Cheong Wai Kwong,Iria Neri
出处
期刊:PubMed
日期:2022-01-01
卷期号:20 (6): 414-419
被引量:2
摘要
Sensitive skin exposed to external insults (i.e., allergens, chemicals, and radiation) becomes erythematosus, and with repeated aggravations may become chronically dry. This is often observed in atopic dermatitis and allergic contact dermatitis, two skin conditions that display key pathogenic components: barrier dysfunction, skewed inflammatory immune response, and pruritus. Recent studies have evidenced that oxidative stress is a possible fourth component of the pathogenesis of sensitive skin. In patients with persistent disease, new agents and combination therapies that target oxidative stress along with other hallmarks of dry and sensitive skin have depicted positive effects on clinical outcomes in infants with dry and sensitive skin. In this paper, we reviewed clinical registration studies of products that have been observed to reduce skin dryness with cosmetically acceptable effects. Overall, similar approaches may be explored to improve the management of dry skin across all age groups for better consistency in achieving treatment goals. (SKINmed. 2022;20:414-419).
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