P3b页
第3A页
神经科学
新颖性
神经影像学
心理学
脑电图
后顶叶皮质
前额叶皮质
现存分类群
事件相关电位
认知
生物
社会心理学
进化生物学
作者
Maryam Soltani,Robert T. Knight
出处
期刊:Critical Reviews in Neurobiology
[Begell House Inc.]
日期:2000-01-01
卷期号:14 (3-4): 26-26
被引量:338
标识
DOI:10.1615/critrevneurobiol.v14.i3-4.20
摘要
A review of the literature investigating the neural origins of detection behavior in humans reveals two event-related potential components, P3a and P3b, each with a distinct neural organization and cognitive function.The P3a is involved in automatic novelty detection and characterized by a more anterior cortical distribution, whereas the P3b is concerned with volitional target detection and has a more posterior cortical distribution. Intracranial investigation, studies with patients with focal brain lesions, and functional neuroimaging (fMRI) studies converge with scalp-recorded event-related potential (ERP) data in suggesting that a widespread cortical network gives rise to both automatic and controlled detection behavior. The main regions consistently attributed to generating detection-related brain activation include the temporal-parietal junction, medial temporal complex, and the lateral prefrontal cortex. The extant human and animal literature addressing the neural networks, neuropharmacological underpinnings, and behavioral significance of the P300 potential will be reviewed.
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