L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea

Here, we report a simple and efficient method for the synthesis of different unsymmetrical N,N'-disubstituted urea and N-substituted urea derivatives using L-Proline as a green catalyst. The methodology is applicable for synthesizing various derivatives of phenylurea, diphenyl urea with excellent yield at mild condition. Keywords: N-substituted urea, urea, amines, N, N`-disubstituted urea, L-Proline, green catalyst.