An Efficient, Selective Hydrolysis of Terminal Isopropylidene Acetal Protection by Zn(NO3)2· 6H2O in Acetonitrile

Di-O-isopropylidene sugar derivatives (1a-9a) on treatment with a solution of Zn(NO3)2 · 6H2O in acetonitrile, undergo regioselective hydrolysis to furnish the corresponding diols (1b-9b) in excellent yields.