Surgical Outcomes of Silent ACTH+ Corticotroph Pituitary Neuroendocrine Tumors: A Multi-Institutional Experience and Review of the Literature

Silent corticotroph PitNETs have high rates of extrasellar growth, often limiting the ability to achieve gross total resection. Recurrence/progression is common, occurring in 13% to 17% of cases within two years, necessitating the need for close postoperative follow-up.