Jinfukang inhibits lung cancer metastasis by regulating T cell receptors

These results suggest that JFK may upregulate the proportion of CD4⁺ T, CD8⁺ T and NKT cells in peripheral blood, reverse the TCR changes caused by tumor metastasis, and promote the infiltration of CD8⁺ T and NK cells in tumor tissues, thereby inhibiting the growth of tumors and ultimately reducing the burden of lung cancer metastasis. This will provide new strategies for developing Chinese herbal medicine to treat metastasis by regulating TCR.