化学
小学(天文学)
萘
光气
电泳剂
有机化学
芴
组合化学
亲电芳香族取代
烷氧基
催化作用
烷基
聚合物
天文
物理
作者
Daniel Picthall,Brian A. Surgenor,Petr Kilián
出处
期刊:Synthesis
[Georg Thieme Verlag KG]
日期:2022-12-07
卷期号:55 (06): 919-926
摘要
Abstract A scalable synthetic route to both primary arylphosphines ArPH2 and aryldichlorophosphines ArPCl2 is reported. The C–P bond formation was performed in a highly regiospecific manner through electrophilic substitution of selected aromatic hydrocarbons (ArH) with phosphorus pentasulfide. The resultant perthiophosphonic anhydrides Ar2P2S4 were then reacted with LiAlH4 to give primary phosphines ArPH2. Subsequent reaction of ArPH2 with phosgene solution gives dichlorophosphines ArPCl2. Each reaction step requires minimum purification and uses commercially available and economical precursors. The scope of the reaction was shown to include alkoxy and phenoxy substituted benzenes as well as naphthalene and fluorene as starting materials.
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