小胶质细胞
转基因小鼠
认知功能衰退
痴呆
内科学
内分泌学
医学
淀粉样蛋白(真菌学)
转基因
早老素
阿尔茨海默病
疾病
心理学
神经科学
病理
化学
炎症
生物化学
基因
作者
Liangwei Wu,Yang Zhao,Xiaokang Gong,Zheng Liang,Jing Yu,Jiaquan Wang,Yuheng Zhang,Xiaochuan Wang,Xiji Shu,Jian Bao
标识
DOI:10.1002/mnfr.202400660
摘要
Our findings demonstrate that IF ameliorates amyloid deposition and cognitive deficits in the AD model mice, which is associated with the reduction of LDs within microglia, providing support for the use of the dietary intervention against AD pathology.
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