Durable CD4 T-Cell Memory Generation Depends on Persistence of High Levels of Infection at an Effector Checkpoint that Determines Multiple Fates

Susan L. Swain1, Michael C. Jones1, Priyadharshini Devarajan1, Jingya Xia1, Richard W. Dutton1, Tara M. Strutt2 and K. Kai McKinstry2 1Department of Pathology, University of Massachusetts Medical School, 368 Plantation Ave, Worcester, Massachusetts 01655, USA 2Immunity and Pathogenesis Division, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida 32827, USA Correspondence: susan.swain{at}umassmed.edu