球体
脚手架
多细胞生物
超分子化学
活力测定
化学
形态学(生物学)
生物物理学
表面改性
纳米技术
癌细胞
细胞
材料科学
体外
癌症
生物医学工程
生物化学
生物
分子
有机化学
物理化学
医学
遗传学
作者
Yuting Wen,Nana Nyarko Mensah,Xia Song,Jingling Zhu,Wen See Tan,Xinwei Chen,Jun Li
摘要
A hydrogel scaffold with a non-fouling but specific cancer cell-adhesive surface was fabricated through surface modification using β-cyclodextrin-based host-guest chemistry. Interestingly, the hydrogel surface not only selectively captured specific cancer cells, but also grew the cells into multicellular spheroids. The spheroids could be released without damaging the cell viability through replacing the host moieties on the scaffold, and the released spheroids showed no changes in size or morphology.
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