碳酸钙-2
并行传输
多酚
化学
原花青素
肠上皮
儿茶素
食品科学
吸收(声学)
单体
上皮
生物化学
磁导率
细胞
聚合物
有机化学
生物
抗氧化剂
材料科学
复合材料
遗传学
膜
作者
Agnieszka Kosińska,Wilfried Andlauer
出处
期刊:Food Chemistry
[Elsevier]
日期:2012-12-01
卷期号:135 (3): 999-1005
被引量:42
标识
DOI:10.1016/j.foodchem.2012.05.101
摘要
Cocoa is an abundant source of polyphenols, mainly flavan-3-ol monomers and polymers. In the literature, there are contradictory data on the absorption limit of procyanidins in humans. In our study, the Caco-2 cell model of intestinal epithelium was used to determine the absorption and secretion of cocoa flavan-3-ols. Three compounds: (+)-catechin, (−)-epicatechin and procyanidin B2 were detected and quantified at the receiver side of Caco-2 monolayer after 2 h transport experiment. The obtained results of apparent permeability coefficient suggest paracellular route of transport of investigated compounds. Additionally, the results suggest that compounds of cocoa powder purified extract are able to affect tight junction functioning.
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