In situ synthesis of Cu–BTC (HKUST-1) in macro-/mesoporous silica monoliths for continuous flow catalysis

The metal-organic framework Cu-BTC has been successfully synthesized as nanoparticles inside the mesopores of silica monoliths featuring a homogeneous macropore network enabling the use of Cu-BTC for continuous flow applications in liquid phase with low pressure drop. High productivity was reached with this catalyst for the Friedländer reaction.