安普克
合成代谢
分解代谢
代谢综合征
代谢途径
AMP活化蛋白激酶
糖尿病
酶
医学
生物信息学
生物
蛋白激酶A
生物化学
内分泌学
作者
Hemant Sharma,Sunil Kumar
标识
DOI:10.2174/0929867323666160406120814
摘要
This review covers recent discoveries of phytoconstituents, herbal extracts and some semi-synthetic compounds for treating metabolic syndrome with AMPK activation as one of their mechanisms of action. Recent researches have demonstrated AMPK activation to ameliorate multiple components of metabolic syndrome by regulating a balance between anabolic and catabolic cellular reactions. The review attempts to delineate the AMPK activation by natural agents from the perspective of its functional consequences on enzymes, transcription factors and signaling molecules and also on other potential factors contributing in the amelioration of metabolic syndrome. Keywords: Cardiovascular disorders, diabetes, obesity, metabolic syndrome, transcription factors, phytoconstituents.
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