炎症体
医学
心脏病学
内科学
信号转导
细胞生物学
心房颤动
炎症
生物
作者
Chunxia Yao,Tina Veleva,Larry Scott,Shuyi Cao,Luge Li,Gong Chen,Prince Jeyabal,Xiaolu Pan,Katherina M. Alsina,Issam Abu-Taha,Shokoufeh Ghezelbash,Corey Reynolds,Ying H. Shen,Scott A. LeMaire,Wilhelm Schmitz,Frank U. Müller,Ali El‐Armouche,N. Tony Eissa,Christine Beeton,Stanley Nattel
出处
期刊:Circulation
[Lippincott Williams & Wilkins]
日期:2018-05-25
卷期号:138 (20): 2227-2242
被引量:626
标识
DOI:10.1161/circulationaha.118.035202
摘要
Our study establishes a novel pathophysiological role for CM NLRP3 inflammasome signaling, with a mechanistic link to the pathogenesis of AF, and establishes the inhibition of NLRP3 as a potential novel AF therapy approach.
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