[Research advances on the role of hemoglobin spray in chronic wounds].

Oxygen plays an important role in the process of wound healing. Researches have shown that more than 97% of chronic wounds are in a state of hypoxia, which is one of the key factors resulting in refractory wounds. Local oxygen therapy is a treatment method that can directly provide oxygen to wounds without relying on the damaged vascular system. It can effectively promote chronic wounds healing by transmitting sufficient oxygen to wounds through specific devices or preparations. Hemoglobin spray is a new form of local oxygen therapy, which has the advantages of good effect, simple operation, and low cost. This article reviews the development, component, safety, oxygen supply principle, and application methods of hemoglobin spray and its effects in the treatment of chronic wounds, so as to provide a new direction for the treatment of chronic wounds.氧气在创面愈合过程中起着至关重要的作用。研究表明，超过97%的慢性创面处于缺氧状态，这是导致创面迁延不愈的关键因素之一。局部氧疗是一种不依赖受损的脉管系统直接向创面供氧的治疗方式，即通过特定的装置或制剂将充足的氧气传输到创面，有效促进慢性创面愈合。血红蛋白喷剂是局部氧疗的一种新形式，具有效果良好、操作简单及成本低等优势。该文就血红蛋白喷剂的发展、组成成分、安全性、供氧原理、使用方法以及在慢性创面治疗中的作用进行综述，为慢性创面治疗提供新方向。.