静脉注射免疫球蛋白
皮疹
医学
抗体
并发症
皮肤病科
器质性脑综合征
免疫学
内科学
精神科
作者
Yan Li,Hui Wang,Aiqin Wang,Guowei Zhao
标识
DOI:10.1111/1346-8138.16994
摘要
Abstract Scleromyxedema (SMX) is a rare disease of unknown cause. It is a chronic, progressive, metabolic disorder characterized by a generalized papular and scleroderma‐like rash, as well as a subtype of lichen myxedematosus. Dermato‐neuro syndrome (DNS) is a rare neurological complication of SMX. It has flu‐like prodromal symptoms; consists of a triad of fever, coma, and seizures; and can be life‐threatening. We describe a patient with SMX complicated by DNS after infection with COVID‐19. Her symptoms resolved after treatment with acyclovir and low‐dose glucocorticoids, suggesting that DNS seizures may have a viral cause. Her skin lesions also improved after seven courses of intravenous immunoglobulin treatment, confirming that intravenous immunoglobulin is effective in these cases.
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