ChemInform Abstract: Convenient Synthesis of Functionalized Spiro[indoline‐3,2′‐pyrrolizines] or Spiro[indoline‐3,3′‐pyrrolidines] via Multicomponent Reactions.

Abstract An uncatalyzed three‐component reaction of 3‐methylene oxindoles, α‐amino acids, and dialkyl acetylenedicarboxylates proceeds with sequential generation of active α,β‐enamino ester and azomethine ylide, followed by 1,3‐dipolar cycloaddition reaction.