微秒
化学
门控
电子转移
毫秒
氧化还原
构象变化
动力学
等离子体子
分子
时间分辨率
细胞色素c
光化学
化学物理
生物物理学
立体化学
光电子学
生物
天文
物理
量子力学
生物化学
有机化学
线粒体
作者
Yan Wang,Hui Wang,Yuheng Chen,Yixian Wang,Hong‐Yuan Chen,Xiaonan Shan,Nongjian Tao
摘要
Conformational fluctuations play a central role in the electron transfer reactions of molecules. Because the fluctuations can be extremely fast in kinetics and small in amplitude, a technique with fast temporal resolution and high conformational sensitivity is needed to follow the transient electron transfer processes. Here we report on an electrochemically controlled plasmonic detection technique capable of monitoring conformational changes in redox molecules with ns response time. Using the technique, we study the electron transfer reaction and the associated conformational gating of a redox protein (cytochrome c). The study reveals that the conformational gating takes place over a broad range of time scales, from microsecond to millisecond.
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