皮肤温度
灌注
体温过低
生物医学工程
医学
持续监测
芯(光纤)
材料科学
麻醉
心脏病学
运营管理
经济
复合材料
作者
Gimin Park,Seungjai Woo,Kyomin Kim,Jiyong Kim,Junphil Hwang,Sang Kyu Kim,Hotaik Lee,So‐Young Lee,Boksoon Kwon,Sungho Kim,Hong-Soon Rhee,Woochul Kim
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2023-07-11
卷期号:8 (8): 2975-2985
标识
DOI:10.1021/acssensors.3c00273
摘要
Core body temperature (CBT) is one of the four vital signs that must be monitored continuously. The continuous recording of CBT is possible through invasive methods by inserting a temperature probe into specific body sites. We report a novel method to monitor CBT through the quantitative measurement of skin blood perfusion rate (ωb,skin). By monitoring the skin temperature, heat flux, and ωb,skin, the arterial blood temperature, equivalent to CBT, can be extracted. ωb,skin is quantitatively evaluated thermally via sinusoidal heating with regulated thermal penetration depth so that the blood perfusion rate is acquired only in the skin. Its quantification is significant because it indicates various physiological events including hyper- or hypothermia, tissue death, and delineation of tumors. A subject showed promising results with steady values of ωb,skin and CBT of 5.2 ± 1.05 × 10–4 s–1 and 36.51 ± 0.23 °C, respectively. For periods where the subject’s actual CBT (axillary temperature) did not fall within the estimated range, the average deviation from the actual CBT was only 0.07 °C. This study aims to develop a competent methodology capable of continuously monitoring the CBT and blood perfusion rate at a distant location from the core body region for the diagnosis of a patient’s health condition with wearable devices.
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