卡宾
芳基
化学
光化学
催化作用
电子转移
可见光谱
组合化学
有机化学
材料科学
烷基
光电子学
作者
Sheng He,Qiang Liu,Beibei Zhang,Zhixiang Wang,Xiangyu Chen
标识
DOI:10.1002/anie.202218468
摘要
Abstract Fluoroarenes are abundant and readily available feedstocks. However, due to the high reduction potentials of mono‐fluoroarenes, their photoreduction remains a continuing challenge, motivating the development of efficient activation modes to address this issue. This report presents the blue light‐induced N‐heterocyclic carbene (NHC)‐catalyzed single electron reduction of mono‐fluoroarenes for biaryl cross‐couplings. We discovered that under blue light irradiation, NHC/ t BuOK combination could construct powerful photoactive architectures to promote single electron transfer for C aryl −F bond reduction via forming highly reducing NHC radical anion. Notably, the strategy was also successful to reduce C aryl −O, C aryl −N, and C aryl −S bonds for biaryl cross‐couplings.
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