The Effects of Age Pupil Diameters at Different Light Amplitudes

Objectives: This study was an evaluation of pupil response at different light amplitudes in healthy individuals in different age groups.Methods: A total of 210 eyes of 105 healthy individuals were included in the study.The participants were divided into 4 groups at 15-year age intervals: 15-30, 31-45, 46-60, and over 60 years.The dimensions of the pupil were measured with a pupillometer at 5 different light amplitudes: 0, 1, 10, 100, and 200 cd/m 2 .The average pupil diameter in the groups was compared and changes in pupil diameter were correlated for each light amplitude according to age.Results: The mean pupil diameter was 4.96+0.82mm in males, and 4.95+0.87mm in females at 0 cd/m 2 light amplitude, and 2.44+0.19mm and 2.40+0.19mm, respectively, at 200 cd/m 2 light amplitude.The differences were not statistically significant (p>0.05).In addition, there was no significant difference in pupil size between the right and left eye at any light amplitude (p>0.05).Pupil diameters were found to be smaller at all light amplitudes with advanced age.There was a negative significant correlation between pupil size and age at all light amplitudes (p<0.05).The correlation was stronger at low light amplitudes.Conclusion: Pupil response to light is influenced by age.This should be taken into consideration when evaluating pupil reaction.