卡斯波芬金
医学
侵袭性念珠菌病
棘白菌素
氟康唑
重症监护室
随机对照试验
米卡芬金
重症监护医学
临床试验
急诊医学
抗真菌
儿科
内科学
皮肤病科
作者
Patrick M. Honorè,Matteo Bassetti,Oliver A. Cornely,Hervé Dupont,Jesús Fortün,Marin H. Kollef,Peter G. Pappas,John Pullman,José A. Vázquez,I Bielicka,Sara Dickerson,Nick Manamley,Taylor Sandison,George R. Thompson
出处
期刊:Critical Care
[BioMed Central]
日期:2024-11-11
卷期号:28 (1)
被引量:2
标识
DOI:10.1186/s13054-024-05152-2
摘要
Invasive candidiasis/candidemia (IC/C) is associated with a substantial health economic burden driven primarily by prolonged hospital stay. The once-weekly IV echinocandin, rezafungin acetate, has demonstrated non-inferiority to caspofungin in the treatment of IC/C. This paper reports a post hoc pooled exploratory analysis of length of stay (LoS) for hospital and intensive care unit (ICU) stays in two previously published clinical trials (ReSTORE [NCT03667690] and STRIVE [NCT02734862], that compared rezafungin with daily IV caspofungin (stable patients in the caspofungin group who met relevant criteria could step down to fluconazole after 3 days or more).
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