化学
IC50型
一氧化氮
阳性对照
原材料
立体化学
核化学
体外
生物化学
传统医学
有机化学
医学
作者
Thi Thu Trang Bui,Bui Thi Mai Anh,Nguyễn Thị,Nguyễn Thị Cúc,Le Thi Huyen,Nhu Thi Hang Nga,Phan Văn Kiệm,Bùi Hữu Tài
标识
DOI:10.1002/cbdv.202401787
摘要
Abstract Four new compounds, suaedamas A–D ( 1 – 4 ), and seven known ones ( 5 – 11 ) were isolated from the aerial parts of Suaeda maritima . Their chemical structures were evaluated by the IR, HR‐ESI‐MS, 1D‐, and 2D‐NMR, experimental and calculated ECD spectra. Compounds 1–6 inhibited nitric oxide production in LPS activated RAW 264.7 cells with IC 50 values ranging from 29.3 to 85.5 μM, compared to that of the positive control compound, dexamethasone, which showed IC 50 value of 13.4 μM.
科研通智能强力驱动
Strongly Powered by AbleSci AI