注意事项
检测点注意事项
软组织
链球菌
医学
抗生素
内科学
微生物学
微生物培养
外科
生物
病理
细菌
遗传学
作者
Ryan M. Close,Catherine G. Sutcliffe,Patrick Galdun,Angelina Reid,Morgan R. Askew,Anne M. Davidson,Kamellia Kellywood,Dennie Parker,Jayshree Patel,Eugene Romancito,Laura B. Brown,James B. McAuley,Laura L. Hammitt
标识
DOI:10.1016/j.diagmicrobio.2022.115729
摘要
Skin and soft tissue infections (SSTIs) are commonly caused by group A Streptococcus (GAS). Rapid molecular assays for detecting GAS in wounds would help with clinical management. This study assessed a point-of-care system for the detection of GAS in non-severe SSTIs in a Native American community in the Southwest.Patients presenting with a new non-severe SSTI were eligible if a swab was collected. The swab was tested by traditional culture methods and using the cobas® Liat® point-of-care (POC) system and results were compared.399 samples were included. The final result from the POC assay was positive for 52.0% of samples. Compared to culture, the POC assay had a sensitivity of 100% and specificity of 99.5%.The cobas® Liat® system accurately and efficiently identified GAS in non-severe SSTIs. Having a POC test available to rapidly identify or rule out GAS could help to minimize overuse of antibiotics.
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