制药工业
化学
生化工程
催化作用
过程(计算)
比例(比率)
医药制造业
有机催化
纳米技术
有机化学
生物技术
计算机科学
工程类
对映选择合成
物理
操作系统
材料科学
生物
量子力学
生物信息学
作者
Carl A. Busacca,Daniel R. Fandrick,Jinhua J. Song,Chris H. Senanayake
标识
DOI:10.1002/adsc.201100488
摘要
Abstract Catalysis has become increasingly important for the pharmaceutical industry. Catalysis is a critical technology that enables economical and environmentally‐sound manufacturing processes. The development of a viable catalytic process for industrial scales is a complex task that requires the collaboration of multiple disciplines. In this article, a number of selected, noteworthy industrial examples are discussed to showcase the catalytic technologies that have been successfully practiced on large scales for active pharmaceutical ingredient (API) synthesis, involving transition metal catalysis, biocatalysis and organocatalysis. In addition, several examples of potential and future catalytic transformations are included which can be utilized in pharmaceutical industry in large‐scale operational settings.
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