医学
急性胰腺炎
入射(几何)
逻辑回归
接收机工作特性
内科学
急诊科
激素
阿帕奇II
曲线下面积
三碘甲状腺素
胰腺炎
促甲状腺激素
阶段(地层学)
队列
胃肠病学
重症监护室
生物
精神科
光学
物理
古生物学
作者
Weiqiang Yang,Qian Yang,Wan Chen,Xiao Bin Zhang,Qingqing Xu,Yun Qiao,Xinhui Xu,Li Liu,Xiaoye Lu,Changqing Zhu
标识
DOI:10.1111/1751-2980.12609
摘要
To investigate the relationship between serum levels of thyroid hormones and disease severity at the early stage of acute pancreatitis (AP).Cohort data from 172 patients with AP attending the Emergency Department of our hospital from 2012 to 2017 were retrospectively reviewed and analyzed. Patients were categorized into mild (MAP), moderately severe (MSAP) and severe AP (SAP) groups based on the disease severity. The MSAP and SAP groups were combined into a non-MAP group for analysis. The predictive values of C-reactive protein (CRP) levels, Ranson score, APACHE II score and serum thyroid hormone levels were analyzed.In total, 76 (44.2%), 85 (49.4%) and 11 (6.4%) patients were included in the MAP, MSAP and SAP groups, respectively. The free triiodothyronine (FT3) levels were significantly lower in the combined non-MAP group than in the MAP group. The tetraiodothyronine (T4) levels were significantly lower in the SAP group than in the MAP and MSAP groups (P = 0.002). Logistic regression analysis revealed that a low FT3 level was an independent risk factor for the incidence of non-MAP (P = 0.004). The area under the receiver operating characteristic curve and sensitivity of FT3 were 0.729 and 88.2%, respectively, which were higher than those of CRP, Ranson and APACHE II scores.Monitoring FT3 levels in the early stage of AP is helpful for evaluating disease severity and predicting the incidence of non-MAP, making it a useful tool for guiding AP treatment.
科研通智能强力驱动
Strongly Powered by AbleSci AI