内科学
内分泌学
妊娠期
生理学
睡眠(系统调用)
子痫前期
胎儿
作者
Min Meng,Yanrui Jiang,Lixia Zhu,Guanghai Wang,Qingmin Lin,Wanqi Sun,Yuanjin Song,Shumei Dong,Yujiao Deng,Tingyu Rong,Qi Zhu,Hao Mei,Fan Jiang
标识
DOI:10.1016/j.sleep.2019.11.1194
摘要
Abstract Objectives To study the impact of maternal sleep in late pregnancy on birth weight (BW) and leptin and lipid levels in umbilical cord blood. Study Design A total of 277 healthy and singleton pregnancy women were recruited for participation in the Shanghai Sleep Birth Cohort Study (SSBC) during their 36–38 weeks of pregnancy, from May 2012 to July 2013. Maternal night sleep time (NST), sleep efficiency (SE), sleep onset latency (SOL) and the percentage of wake after sleep onset (WASO) in NST and midpoint of sleep (MSF) were measured by actigraphy for seven consecutive days. The leptin and lipid levels were determined in cord blood samples collected from the umbilical vein immediately after delivery. Birth information (birth weight, gender, delivery type, etc.) was extracted from medical records. A multivariable linear regression model was applied to examine the effect of maternal sleep in late pregnancy on newborn leptin and lipid levels in umbilical cord blood. Results A total of 177 women and their infants were included in the analysis. Maternal mean NST was 7.03 ± 1.10 h in late pregnancy, and 48% had a shorter sleep time (NST Conclusions Short sleep duration and poor sleep quality during late pregnancy were associated with newborn leptin and lipid levels, and efforts on improving maternal sleep during late pregnancy should be advocated for children’s health.
科研通智能强力驱动
Strongly Powered by AbleSci AI