化学
光延反应
克莱森重排
复分解
烯烃复分解
有机化学
产量(工程)
苯酚
序列(生物学)
盐变质反应
组合化学
聚合
生物化学
冶金
材料科学
聚合物
作者
О. А. Лозинский,J. Bistodeau,Catherine Bennetau-Pelissero,V. P. Khilya,Svitlana Shinkaruk
标识
DOI:10.1007/s00706-020-02584-8
摘要
The multistep synthesis of a prenylneoflavone through a sequence of the Mitsunobu reaction/Claisen rearrangement/olefin cross-metathesis reaction has been accomplished in 5% yield over six steps starting from commercially available 3-methoxyacetophenone. The sequence is shown to be compatible with a Pechmann condensation which proved to be a robust and cost-effective method for the assembling of the α-pyrone core. The results open doors to a general approach to the prenylneoflavone system starting from phenol and acetophenone derivatives.
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