Multi-omics strategies and applications for the degradation of pollutants by microbiome

The wide distribution and metabolic flexibility of microorganisms in nature endow them with the capacity to degrade large amounts of xenobiotic substances. Human production activities release a variety of xenobiotic pollutants into the soil, water and atmosphere causing serious environmental pollution problems. Xenobiotic contaminants are partially or completely mineralized by the combination of metabolic collaboration among microbiome and environmental factors. Traditional pollutant degradation studies are based on isolation and culture of microorganisms, while high-throughput strategies such as metagenome, metatranscriptome, metaproteome and metabolome provide technical support to investigate pollutant degradation and ecological remediation by microbiome. This article mainly introduces the applications of different omics in exploring the microbiome in pollutant degradation and ecological restoration.