材料科学
折射率
光学
法布里-珀罗干涉仪
表面等离子共振
生物传感器
检出限
表面等离子体子
谐振器
光电子学
波长
等离子体子
纳米技术
统计
物理
数学
纳米颗粒
作者
Haibo Wu,Hui Huang,Min Bai,Pengbo Liu,Ming Yu Chao,Jie Hu,Jian Hao,Tun Cao
出处
期刊:Optics Express
[The Optical Society]
日期:2014-12-18
卷期号:22 (26): 31977-31977
被引量:13
摘要
An all glass optofludic biosensor with high quality-factor Fabry-Perot cavity (FPC) channel was reported. The all glass sandwich structure can completely eliminate the etching roughness of the channel surface, and can extend the operating wavelength to visible and ultraviolet regions compared with that of Si-based sensor. The quality-factor of the FPC channel is 875, and the system noise can be reduced to 1.2 nV by combining optical differential detection with phase lock-in detection. A detection limit of 15ng/mL for glucose solution, which corresponds to a refractive index unit of 2.0 × 10-9, was experimentally demonstrated. The all glass FPC sensor features low cost and robust compared with surface-plasmon-resonance sensor and ring-resonator sensor.
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