材料科学
药物输送
黏膜黏附
海藻酸钠
丙烯酸聚合物
聚合物
丙烯酸
聚合
丙烯酸树脂
粘附
化学工程
纳米技术
高分子化学
高分子科学
钠
毒品携带者
复合材料
共聚物
单体
涂层
冶金
工程类
作者
Paola Laurienzo,Mario Malinconico,Giuditta Mattia,R. Russo,Maria Immacolata La Rotonda,Fabiana Quaglia,Donatella Capitani,Luisa Mannina
摘要
Abstract The aim of the present work was to develop a family of novel materials based on a combination of sodium alginate and acrylic polymers and to evaluate their potential in drug delivery applications. In the presence of sodium alginate, acrylic chains with acidic as well as basic moieties were polymerized to create an interpolymer complex based on electrostatic interactions that are able to modulate the release rate of low molecular weight drugs. The synthesized materials were used to prepare hydrophilic matrices for drug delivery and tested for their adhesion properties to glass, used as a model substrate for mucoadhesion. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res, 2006
科研通智能强力驱动
Strongly Powered by AbleSci AI