单核细胞
兴奋剂
阳离子脂质体
TLR7型
脂质体
阳离子聚合
免疫学
受体
药理学
化学
医学
Toll样受体
先天免疫系统
生物化学
转染
基因
有机化学
作者
Pia T Johansen,Daniel Zucker,Ladan Parhamifar,Houman Pourhassan,Ditte Villum Madsen,Jonas R. Henriksen,Monika Gad,Alcide Barberis,Roberto Maj,Thomas L. Andresen,Simon S Jensen
标识
DOI:10.1517/17425247.2015.1009444
摘要
Our present liposomes selectively target monocytes in fresh blood, enabling delivery of TLR7 agonists to the intracellular TLR7 receptor, with subsequent monocyte activation and boost in secretion of proinflammatory cytokines. We envision this technology as a promising tool in future cancer immunotherapy.
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