内皮功能障碍
血管性血友病因子
医学
血管生成
炎症
不对称二甲基精氨酸
内皮祖细胞
血管生成素
祖细胞
免疫学
内皮
内科学
内皮干细胞
血管内皮生长因子
血小板
干细胞
生物
细胞生物学
体外
氨基酸
血管内皮生长因子受体
精氨酸
生物化学
出处
期刊:Current Vascular Pharmacology
[Bentham Science]
日期:2020-12-31
卷期号:19 (3): 243-249
被引量:32
标识
DOI:10.2174/1570161118666200421142542
摘要
Vascular diseases are the main reason for morbidity and mortality worldwide. As we know, the earlier phase of vascular diseases is endothelial dysfunction in humans, the endothelial tissues play an important role in inflammation, coagulation, and angiogenesis, via organizing ligand-receptor associations and the various mediators’ secretion. We can use many inflammatory non-invasive tests (flowmediated dilatation, epicedial fat thickness, carotid-intima media thickness, arterial stiffness and anklebrachial index) for assessing the endothelial function. In addition, many biomarkers (ischemia modified albumin, pentraxin-3, E-selectin, angiopoietin, endothelial cell specific molecule 1, asymmetrical dimethylarginine, von Willebrand factor, endothelial microparticles and endothelial progenitor cells) can be used to evaluate endothelial dysfunction. We have focused on the relationship between endothelial dysfunction and inflammatory markers of vascular disease in this review.
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