Unraveling the immune axis of ocular surface microbiota in keratoconus

Purpose of review This review's objective is to give readers an update on recent and developing information about the function of the ocular surface microbiome in keratoconus. Recent findings The microbiome's function in the pathogenesis of keratoconus is supported by recent research. Numerous metabolites that are produced by the ocular surface bacteria can affect the host tissue. A shift in the microbiota may influence the composition of these metabolites, which could have an effect on keratoconus by altering the cornea's metabolic environment. Summary Gaining insight into the function of the ocular surface microbiota in keratoconus could open up new avenues for the creation of new therapeutic modalities.