吡啶
化学
废止
磷化氢
重氮
位阻效应
吲哚嗪
芳基
药物化学
溴化物
有机化学
催化作用
烷基
作者
Simin Sun,Yuliang Wei,Jiaxi Xu
摘要
Chemoselective annulations of phosphoryl carbenes generated from diazo(aryl)methyl(diaryl)phosphine oxides with pyridinium 1,4-zwitterionic thiolates were performed under microwave irradiation, affording 1-diarylphosphoryl-1H-benzo[c]thiopyran derivatives via [3+3] annulation and indolizine derivatives via ([1+5]-1) annulation with P-Cope elimination as the key step. The annuloselectivity was controlled by the steric hindrance of pyridiniums in pyridinium 1,4-zwitterionic thiolates.
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